Funded Publications
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1964
Evaluation of lymphocyte transfer test in normal and uraemic subjects
+1
Nelson S D, McGeown M
1965
An effect of D-glucose on platelet stickiness
+2
Dalby A M, Millar J H D, Weaver J A
1965
Comparision of Lymphocyte-transfer test and white-blood-cell grouping for organ donor selection.
+1
Bridges J M, McGeown M
1965
Effect of Uracil Mustard on the homograft response in rabbits.
+0
Bridges J M
1965
Foetal liver suspensions in the treatment of marrow aplasia
+2
Bridges J M, Edelstyn G J A, Lyons A R
1965
Simultaneous free and bound radioactive vitamin B12 urinary excretion test.
+1
Bridges J M, Nelson M G
1966
Effect of Quinidine and related compounds on uptake and release of Serotonin by blood platelets
+0
Baldini M
1967
The effect of ‘in-vivo’ alteration of free fatty acids on platelet stickiness
+3
Dalby A M, Hadden D, Johnston H, Weaver J A
1967
Urinary amino acid excretion in subjects with leukaemia
+1
Neill D W, Bridges J M
1968
L_asparaginase activity in human and animal sera.
+0
Bridges J M
1968
L-asparaginase activity in human and animal sera
+0
Bridges J M
1968
The in vitro uptake of 35S L -methionine by normal and leukaemic leucocytes
+0
Bridges J M
1969
Distribution of amino acids in urine, plasma, leucocytes and erthrocytes of leukaemic and normal subjects.
+1
Bolger C D, Bridges J M
1969
The influence of human serum on the anti-tumour activity of two L-asparaginases
+1
Niblock R M, Bridges J M
1970
Immunosuppressive activity of L-asparaginase in mice.
+1
Lee M B, Bridges J M
1971
An unusual case of chronic granulocytic leukaemia
+1
Nevin N C, Bridges J M
1971
Dysgammaglobulinaemia complicated by disseminated measles.
+7
Allen I, Beare M, Bridges J M, Connolly J H, Haire M, Nevin N C, Neill D W, Hobbs J
1971
Factors influencing the ‘in vitro’ enhancement of L-asparaginase activity.
+1
Bolger C D, Bridges J M
1973
The total N-acetyl neuraminic acid content of human, normal and lymphatic leukaemic lymphocytes
+0
Bridges J M
1974
Characteristics of colony growth from normal human bone marrow.
+1
McNeill T A, Bridges J M
1974
The effect of Prednisolone on Lysosomes of the P.1798 Lymphosarcoma
+0
Bridges J M
1975
Fanconic’s aplastic anaemia with short stature. Absence of response to human growth hormone.
+1
Bridges J M, Hadden D
1975
Inhibition of normal human in vitro colony formation in acute leukaemia patients
+1
McNeill T A, Bridges J M
1975
Quantitative Nitroblue Tetrazolium test in mongolism
+1
Bridges J M, Nevin N C
1975
Reactivation of scabies rash by methotrexate
+1
Bridges J M, Morris T C M
1977
Changes in granulopoiesis detected by in vitro colony formation in acute lymphatic leukaemia
+3
Butler M, Muldrew J G, McNeill T A, Bridges J M
1978
Inhibitor of in vitro granulopoiesis in plasma of patients with renal failure.
+2
Sutehrland R, Morris T C M, Chapman G V
1978
The expanding spectrum of auto—immune blood disorders
+1
Morris T C M, Vincent P C
1979
An appraisal of Phosphatase N as a marker for chronic lymphatic leukaemia
+2
Murphy R F, Bridges J M, Elmore D T
1979
Bone marrow necrosis in a case of chronic myeloid leukaemia
+0
Morris T C M
1979
Haemopoietic inhibitors in acute leukaemia
+0
Morris T C M
1979
N-acetyI-D glucosaminidose activity in normal and chronic lymphocytic leukaemic lymphocytes
+1
Lewis M H R, Bridges J M
1980
A comparison of∞ —L-fucosidose activity in normal and chronic lymphocytic leukaemic lymphocytes
+1
Bridges J M, Lewis M H R
1980
Absorption of methotrexate under standardised conditions in children with acute lymphoblastic leukaemia.
+3
Welshman S G, Dempsey S I, Bridges J M, Glasgow J F T
1980
An estimation of β—glucuronidase and N-acetyl-β-glucosaminidase activity in normal and chronic lymphocytic leukaemia lymphocytes
+1
Crockard A D, Bridges J M
1980
Can food influence the absorption of methotrexate in children with acute lymphoblastic Ieukaemia?
+2
Welshman S G, Glasgow J F T, Bridges J M
1980
Development of a Radiochemical assay for Glycyl—leucine Dipeptidase in human B and T lymphocytes
+3
Kelly G J C, Murphy RF, Elmore DT, Bridges J M
1980
Does methotrexate impair its absorption in children with acute lymphoblastic leukaemia?
+2
Welshman S G, Glasgow J F T, Bridges J M
1980
Inhibition of normal human granulopoiesis in vitro by Non B Non T lymphocytes
+2
Vincent P C, Sutherland R, Heasey P
1980
Lysosomal enzyme levels in a case of T cell chronic lymphatic leukaemia
+1
Morris T C M, Bridges J M
1981
Auto—anti—B in a patient with Acute Leukaemia
+3
Bradley A, Morris T C M, Burnside P, Robertson J H
1981
Enterotoxic effect of methotrexate: Does it influence the drugs absorption in children with acute lymphoblastic Ieukaemia?
+2
Welshman S G, Glasgow J F T, Bridges J M
1981
Polycythaemia rubra vera in in monozygotic twins
+3
Salmon D, Humphrey C, Robertson J H, Morris T C M
1981
Small bowel enterocyte abnormalities caused by methotrexate therapy in acute lymphoblastic disease of childhood.
+3
Pinkerton C R, Glasgow J F T, Sloan J M, Bridges J M
1981
Three Pyruvate Kinase Variants with Increased Affinity for PEP
+2
Lappin T R J, Lawson B E, Bridges J M
1982
A Rapid Method for Identification of Surface Antigens on Fixed Cells Using Monoclonal Antibodies
+2
Alexander H D, Morris T C M, Robertson J
1982
Cytochemistry of Acid Hydrolases in Chronic B and T Cell Leukaemias
+2
Chalmers D, Matutes E, Catovsky D
1982
Human Umbilical Cord Conditioned Medium: A Source of Pure Granulopoietic Colony Stimulating Activity
+2
Alexandra E Irvine, Hilary Kennedy, J M Bridges
1982
Inhibitory Cells in Aplastic Anaemia
+0
Vincent P C
1982
T—ceIl lymphoma—leukaemia in blacks: A distinct entity
+8
Bourikas G, Lister A, Lampert I, Bridges J M, Rose M, Goolden A W G, McCluskey D R, Greaves M F, Galton D A G
1982
T-cell Iymphoma-leukaemia and hypercalcaemia in West Indians
+6
Greaves M F, McCluskey D R, Lister A, Goolden A W, Rose M, O’Brien M, White J
1982
The in vitro effect of adenine on pyruvate kinase deficient red cells
+3
Elder G E, Savage G A, Cooke P J, Bridges J M
1982
Treatment of Widespread Infiltration in Acute Myeloblastic Leukaemia with Superficial Penetrating Whole Body Electron Beam Therapy
+3
Vincent P C, Foster K M, Johnston N M, Thompson I L
1983
Morphological and Cytochemical Features of Adult T-Cell Lymphoma-L eukaemia
+4
O’Brien M, Robinson D, Tavares de Castro J, Matutes E, Catovsky D
1983
Cancer Chemotherapy alters Plasma Concentration of Immunoreactive Calcitonin
+3
Desai Z R, Ardill J F S, Bridges J M, Buchanan K D
1983
CFU-C in Normal and Leukaemic Grantulopoiesis
+2
T C M Morris, H Kennedy, J M Bridges
1983
Correlation of lymphocyte B-glucuronidase and N—acetyl—B—glucosaminidase with E Rosette Formation
+2
Macfarlane E, Jess H, Catovsky D
1983
Cytochemistry of Normal Lymphocyte Subsets Defined by Monoclonal Antibodies and Immunocolloidal Cold.
+0
Catovsky D
1983
Diagnostic Features of Adult T. Cell Lymphoma-Leukaemia.
+7
O’Brien M, O’Brien C, Lampert I, Crockard A D, Johnson S E, Francis G E, Sharp J, Calton D A G
1983
Distribution of Vasoactive Intestinal Polypeptide Immunoreactivity (VIP—IR) in Leucocytes.
+3
Madden M, Ardill J E S, Buchanan K D, Bridges J M
1983
IgA Pyroglobulinaemia in Lymphoma
+3
Morris T C M, Hayes D, Humphrey C A, Robertson J H
1983
Leukaemia/Lymphoma Cells in CSF
+2
Markey G M, Alexander H D, Morris T C M
1983
Metabolism of Exogenous Adenine in a Pyruvate Kinase-Deficient patient
+2
Elder G E, Savage G A, Bridges J M
1983
Quantitative and Qualitative Deficiency of T-Lymphocyte Colony Formation in T-Cell Lymphoma-Leukaemia.
+1
T C M Morris, D R McCluskey
1983
Stable E Rosette-forming Lymphocytes in the Peripheral Blood in Non-Hodgkin’s Lymphoma.
+3
Alexander H D, Hayes D McG, Robertson J H, Morris T C M
1983
The Ultrastructural Morphology of T Lymphocytes in B-Chronic Lymphocytic Leukaemia: A Study with the OKT3 Monoclonal Antibody and the Immunogold Technique.
+1
Crockard A D, Catovsky D
1983
Ticarcillin Induced Neutmpaenia Corroborated by In Vitro CFU-C Toxicity
+2
T C M Morris, C J Kelly, N McCracken
1983
Ultrastructural Cytochemistry of Chronic T-Cell Leulcaemias: A Study with Four Acid Hydrolases
+2
Crockard A D, O'Brien M, Catovsky D
1983
Vasoactive Intestinal Polypeptide as a Biochemical Marker for Polymorphonuclear Leucocytes.
+3
Johnston C F, Ardill J E S, Buchanan K D, Bridges J M
1983
Vertical migration of Peptide—secretory cells in rat intestinal epithellum
+1
C F Shaw C, Buchanan K D
1983
Vincristine—induced Abnormalities of Gastrointestinal Endocrine Tissue in Rats.
+0
Buchanan K D
1984
A Radiochemical Assay for Lysosomal Carboxypeptidase A in Human B- and T-Lymphocytes
+2
R F Murphy, J M Bridges, D T Elmore
1984
Circulating T Cell Subpopulations in Lithium-Associated Granulocytosis.
1984
Cyto chemistry of Lymphoid Cells: A Review of Findings in the Normal and Leukaemic State.
1984
Depletion of T Lymphocyte Subsets Using Monoclonal Antibody and Complement: Effect on T Colony Formation
+2
Kelly C J, Morris T C M, Bridges J M
1984
Dipeptidylaminopeptidase IV Activity in Normal and Leukemic T-Cell Subpopulations
+3
Macfarlane E, Andrews C, Bridges J M, Catovsky D
1984
Human Umbilical Cord Conditioned Medium (HUCCM). A Stimulus for Human CFU-G
+3
T C M Morris, H Kennedy, G B Wisdon, J M Bridges
1984
Prolymphocytic leukaemia of a B and T Cell Type: Morphological Differences by Light and Electron Microscopy
+3
E Matutes, A D Crockard, M O’Brien, C Costello
1985
The influence of leucocytes and plasma on red cell filtration (Red cell deformability).
1985
Acid hydrolase activities in B-cell chronic lymphocytic leukaemia lymphocytes; Correlation of cytochemical reactions with immuno
+6
Macfarlane E, Markey G M, McConnell R E, Alexander H D, Agnew A N D, Morris T C M, Bridges J M
1985
Amoxycillin Induced Pancytopenia
+1
Agnew A D, Morris T C M
1985
Can food affect the absorption and disposition of chlorambucil in patients with malignant haematological disorders?
+1
Bridges J M, Desai Z R
1985
Determination of Plasma Chlorambucil by Reversed Phase High Performance Liquid Chromatography
+2
Burns D T, Crockard A D, Harriott M
1985
Dipeptidyl amino peptidase IV (DAP IV) in B and T cell leukaemias
+2
Crockard A D, San Miguel J F, Catovsky D
1985
Evidence Following Splenic Radiotherapy for a Highly Dynamic Traffic of CF U—C Between the Spleen and Other Organs in Chronic Granulocytic L eukaemia
+5
Vincent P C, Gunz F W, Sutherland R, Zbroja R, Irvine A E, Forrest P R
1985
Increased Plasma Glycosidase and Protease Activity in Uraemia. Possible Role in the Aetiology of the Anaemia of Chronic Renal Failure
+4
Lappin T R J, Elder G E, Roberts G M, McGeown M G, Bridges J M
1985
Inhibition of T-Lymphocyte Colony Formation by Lymphocytes from Patients with Aplastic Anaemia
+2
Morris T C M, Irvine A E, Alexander H D
1985
Interaction between Lithium and Lymphocytes in Haematopoietic Control
+5
Crockard A D, Desai Z R, Ennis K T, Fay A C, Morris T C M, Bridges J M
1985
Lymphocytes from Patients Receiving Lithium do not Inhibit CF U-C Growth
+5
Crockard A D, Desai Z R, Ennis K T, Fay A C, Morris T C M, Bridges J M
1985
Modified Extraction and Chromatography for the Measurement of Plasma Melphalan by Ion Pair High Performance Liquid Chromatography.
+3
Burns D T, Crockard A D, Desai Z R, Harriott M
1985
Partial identification of a factor produced by non-adherent mononuclear cells which inhibits normal granulopoiesis
+0
Morris T C M
1985
Renal function in the ellimination of oral melphalan in patients with multiple myeloma
+1
Bridges J M, Desai Z R
1985
Separation of Erythropoietic Stimulators in Severe Anaemia using High Performance Gel Permeation Chromatography.
+2
Eldger G E, Madden M, Bridges J M
1985
Successful Remission Induction with Deoxycoformycin in ElderLy Patients with T-Helper Prolymphocytic Leukaemia
+4
Ennis K T, Morris T C M, Robertson J H, Markey G, Alexander H D
1985
The effect of Transferrin Saturation on the Estimation of Erythgropoietin by the Mouse Spleen Cell Microassey
+4
Elder G E, McKibben S H, McNamee P T, McGeown M G, Bridges J M
1986
Enumeration of Absolute Numbers of T Lymphocyte Subsets in B-Chronic Lymphocytic Leukoemia Using an Immunoperoxidase Technique; Relation to Clinical Stage
+7
Alexander H D, Agnew A N D, McConnell R E, Morris T C M, Robertson J H, Patterson C C, Crockard A D, Bridges J M
1986
Esterase and negative monocytes – ? A familial condition
1986
In vitro bioassay of erythropoietic activity in serum using mouse spleen cells. The effect of heat inactivation on serum erythropoietin.
+3
Shannon J S, Lappin T R J, Taylor T, Bridges J M
1986
Prognosis in T Prolymphocytic Leukaemia
1986
Response of Leukaemic Cells to In Vitro Stimuli: A Study of the Activity of Human Umbilical Cord Conditioned Medium, Human Placenta Conditioned Medium and Feeder Layers.
+2
Morris T C M, Kennedy H, J M Bridges
1986
Reversed-phase High-performance Liquid Chromatography of Plasma Melphalan and Chlommbucil: Comparison of Three Detection Methods
+1
Thorburn Burns D, Harriott M
1986
Studies on the mechanism of gastrointestinal absorption of melphalan and chlorambucil.
+0
McElnay J C
1986
Surgery and haemostasis
1986
The anaemia of chronic renal failure: A potentially treatable catabolic phenomenon?
+0
Lappin T R J
1986
The effect of dietary amino acids on the gastrointestinal absorption of melphalan and chlommbucil
+0
McElnay J C
1986
Totally implantable venous access in small children
1986
Upper limb venous thrombosis complicating amyloidosis
+2
Kirk S, Callender M E, iWayne E E
1987
Auto-immune neutropenia and hemolytic anaemia.
+0
Morris T C M
1987
Lymphocyte mediated suppression of granulopoiesis
+1
Irvine A E, French A M
1987
Pathology of the heart and conduction system in lymphoma and Ieukaemia.
1987
T lymphocyte colony formation by lymphocytes from patients with aplastic anaemia.
+2
Morris T C M, Irvine A F, Alexander K D
1987
The CFU-C assay in patients with neutropenia and, in particular, drug associated neutropenia.
+0
Irvine A E
1987
The effect of heat—treatment on the estimation of bioactive erythropoietin in serum using the mouse spleen cell assay.
+3
Elder G E, Shannon J S, Taylor T, Bridges J M
1987
The effect of renal transplantation on serum peptides.
+2
Lappin T R J, Elder C E, Bridges J M
1988
Normal unstimulated lymphocytes produce granulopoietic inhibitory activity.
+2
Irvine A E, Morris T C M, Bridges J M
1988
Red cell pyrimidine 5 nucleotidase deficiency: determination of nucleotidase activity and nucleotide content using HPLC.
+2
Elder G E, Lappin T R J, Bridges J M
1989
Application of the polymerase chain reaction (PCR) to investigate G-CSF expression.
+2
Irvine A E, Brisco M J, Bridges J M
1989
Bone marrow suppression secondary to carbamazepine.
1989
CFU-GM Inhibitors in Neutropenia.
+0
Irvine A E
1989
Detection of carriers of Haemophilia A by restriction fragment length polymorphisms.
+0
Mayne E E
1989
Immunoglobulin light chains in common acute lymphoblastic Ieukaemia.
1989
Serum erythropoietic activity in acute anaemia — An animal model.
+3
Lappin T R J, Elder G E, Taylor T, Bridges J M
1989
The effect of hypobaric hypoxia on misonidazole binding in normal and tumour—bearing mice
+2
Maxwell A P, Abram W P, Bridges J M
1989
The initiation of erythropoietin following renal transplantation.
+4
Lappin T R J, Elder G E, Taylor T, Bridges J M, McGeown M G
1990
An analysis of circulating CD4 lymphocyte subpopulations in B-Cell chronic lymphocytic leukaemia.
+5
Alexander H D, Stephenson C F, Desai Z R, Morris T C M, McNeill T A, Bridges J M
1990
Clearance of severe psoriasis after allogenic bone marrow transplantation.
+0
Jones F G C
1990
Constitutive production of cytokines by umbilical cord fibroblasts.
+1
Irvine A E, Bridges J M
1990
Construction of polyethylene glycol (PEG) modified granulocyte-macrophage colony stimulating factor (GM-CSF) with conserved biological activity.
1990
Dissociation of the proliferation and a differentiation stimuli of granulocyte colony-forming stimulating factor (G-CSF).
1990
Dissociation of two biological activities of granulocyte-macrophage colony stimulating factor (GM-CSF) by polyethylene glycol (PEG).
1990
Effect of recombinant human erythropoietin on anaemia caused by murine mammary carcinoma.
+1
Elder G E, Bridges J M
1990
Erythropoietin production in kidney tubular cells
+1
Lappin T R J, Bridges J M
1990
Isolation, culture and characterisation of fibroblast-like cells derived from Wharton’s jelly portion of the human umbilical cord.
+1
Irvine A E, Ennis K T
1990
Prospective in vitro testing for druginduced neutropenia in a patient requiring anti-malarial prophylaxis: Confirmation of findings on exposure of a patient to drugs.
+0
Morris T C M
1990
Serum peptides and protease activity following renal transplantation.
+2
Lappin T R J, Elder G E, Bridges J M
1990
The metabolism of erythropoietin in the normal and uraemic rabbit.
+2
Lappin T R J, Elder G E, Bridges J M
1990
The molecular genetic analysis of haemophilia A: A directed-search strategy for the detection of point mutations in the human factor VIII gene.
+0
Mayne E E
1990
Trap positive splenic lymphoma – A relatively benign condition occurring in a time-space cluster?
1991
Erythropoietin deficiency in the anaemia of chronic disorders.
+0
Lappin P R J
1991
Evidence for impaired erythropoietin response to anaemia in rheumatoid disease
+0
Lappin T R J
1991
Human immunodeficiency virus infection in Northern Ireland 1980-1989
1991
Hypobaric hypoxia enhances the anti—tumour effect of RSU 1069.
+2
McKeown S R, Lappin T R J, Bridges J M
1991
Lactoferrin inducible monocyte cytotoxicity defective in esterase deficient monocytes
1991
Lactoferrin-inducible monocyte cytotoxicity for K562 cells and decay of natural killer lymphocyte cytotoxicity
1991
Normal unstimulated lymphocytes produce – granulopoietic inhibitory activity
+3
French M A, Bridges J M, Desai Z R, Morris T C M
1991
Production of erythropoietin by kidney tubular cells.
+0
Bridges J M
1991
Recombinant human erythropoietin treatment of tumour—induced anaemia: Effects on tumour growth rate and radiosensitivity.
+2
McKeown S R, Lappin T R J, Bridges J M
1991
Successful treatment of neonatal purpura fulminans with epoprostenol
1991
The proliferative activity of B-chronic lymphocytic Ieukaemia lymphocytes prior to and after stimulation with TPA and PHA.
+1
Desai Z R, Bridges J M
1992
Cytokine-mediated K1-67 expression in Bcell chronic lymphocytic leukaemia lymphocytes
+0
Desai Z R
1992
Disorders of Haemostasis in Diabetes
1992
Polyethylene glycol (PEG) modification of granulocyte macrophage colony stimulating factor (GM-CSF) enhances neutrophil priming activity but not colony stimulating action.
1993
Characterisation of granulopoietic inhibitory activity.
+2
Irvine A E, Morris T C M, Graham G J
1994
A derivative chromosome 14 resulting in partial trisomy of chromosome 12 in B-cell Chronic Lymphocytic Leukemia
+2
Bailie K E M, Jess H, Desai Z R
1994
Analysis of disulphide bonding patterns in human and murine erythropoietin by in vitro mutagenesis.
+4
Winter P C, Hodges V M, McHaIe C M, Elder G E, Goldwasser E
1994
Drug induced neutropenia due to direct effects on CFU-G – 10 years of culture experience
+3
French M A, Daly A T, Ranaghan L, Morris T C M
1995
Relationship between presences of apoptotic cells and cell growth patterns in Myelodysplasia.
+3
Buckley 0, Somerville L E, Roddy S, McMullin M F
1995
Retroviral mediated gene transfer of the human erythropoietin gene into a factor dependant cell line, TF-1.
+2
Winter P C, Lappin T R J, McMullin M F
1995
Screening for erythropoietin receptor mutations in patients with myeloproliferative disorders.
+2
Winter P C, Lappin T R J, McMullin M F
1997
Analysis of the effect of prior therapy on progenitor cell yield: use of a chemotherapy scoring system
+7
Ranaghan, T C M Morris, L Nolan, Z R Desai, A E Irvine, A Jordan, K Magill, S Price
July 1997
Recombinant human erythropoietin and the anaemic horse: flogging a dead horse?
+0
Maxwell AP
July 1997
Selective block in erythropoietin-induced differentiation of growth factor-independent retrovirally-infected TF-1 cells.
+2
Lappin TR, Buckley OM, McMullin MF
October 1997
Sequence analysis of the 3′ hypoxia-responsive element of the human erythropoietin gene in patients with erythrocytosis
+1
McMullin MF, Lappin TR
February 1998
Erythrocytosis due to a mutation in the erythropoietin receptor gene
+6
McMullin MF, Roques AW, Westwood NB, Acharya J, Hughes AE, Lappin TR, Pearson TC
May 1998
Familial hemolytic anemia due to Hb Sabine [beta 91(F7)Leu-Pro] identified by polymerase chain reaction.
+3
Winter PC, McHale CM, Lappin TR, Mayne EE
April 1998
Hemoglobin Old Dominion/Burton-upon-Trent, beta 143 (H21) HisTyr, codon 143 CACTAC–a variant with altered oxygen affinity that compromises measurement of glycated hemoglobin in diabetes mellitus: structure, function, and DNA sequence
+14
Lappin TR, Horne AB, Fairbanks VF, Jones RT, Winter PC, Green BN, Hoyer JD, Reynolds TM, Shih DT, McCormick DJ, Kubik KS, Madden BJ, Head CG, Harvey D, Roberts NB
November 1998
Sequence characterisation and expression of homeobox HOX A7 in the multi-potential erythroleukaemic cell line TF-1.
+4
Bremner P, McMullin MF, Maxwell AP, Winter PC, Lappin TR
August 1999
Erythroblasts from friend virus infected- and phenylhydrazine-treated mice accurately model erythroid differentiation
+1
Winter PC, Lappin TR
March 1999
Erythroid gene expression is differentially regulated by erythropoietin, haemin and delta-aminolaevulinic acid in UT-7 cells.
+1
Winter PC, Lappin TR
June 1999
Erythropoietin production: evidence for multiple oxygen sensing pathways.
+4
Elder GE, Savage GA, Winter PC, Maxwell AP, Lappin TR
June 1999
Regulation of erythropoietin gene expression depends on two different oxygen-sensing mechanisms.
+5
McHale CM, Savage GM, Price S, Winter PC, Maxwell AP, Lappin TR
October 2000
High bax expression is a good prognostic indicator in acute myeloid leukaemia.
+4
McMullin MF, Bailie KE, Lappin TR, Jones FG, Irvine AE
March 2001
Characterization and localization of an erythropoietin-induced gene, ERIC-1/TACC3 identified in erythroid precursor cells.
+7
Hodges VM, Mullan RN, Maxwell P, Simpson D, Thompson A, Winter PC, Lappin TRJ, Maxwell AP
July 2001
Cord blood transferrin receptors to assess fetal iron status
+3
Savage GA, Tubman R, Lappin TR, Halliday HL
September 2001
Differential manipulation of the renin angiotensin system and epoietin requirements in maintenance haemodialysis patients.
+2
Stewart L, Leary J, Lappin TR
June 2001
Homocysteine and methylmalonic acid as indicators of folate and vitamin B12 deficiency in pregnancy
+4
Young PB, Bailie KE, Savage GA, Lappin TR, White R
March 2001
Peptide leucine arginine, a potent immunomodulatory peptide isolated and structurally characterized from the skin of the Northern Leopard frog, Rana pipiens
+10
Cross LJ, Irvine AE, Lappin TR, Dathe M, Krause G, Canning P, Thim L, Beyermann M, Rothemund S, Bienert M, Shaw C
January 2001
Study of maternal influences on fetal iron status at term using cord blood transferrin receptors.
+3
Savage G, Tubman TR, Lappin TR, Halliday HL
July 2002
AINT/ERIC/TACC: an expanding family of proteins with C-terminal coiled coil domains.
+4
Mullan RN, Stewart JP, Morgan NA, Thompson A, Maxwell AP
2002
EPO’s Alter Ego: Erythropoietin has multiple Actions.
+1
Maxwell AP, Johnston PG
November 2002
Familial idiopathic methemoglobinemia revisited: original cases reveal 2 novel mutations in NADH-cytochrome b5 reductase.
+4
Gillespie MJS, Savage G, Hughes AE, McMullin MF, Lappin TRJ
2002
The endogenous granulocyte colony-stimulating factor response following autologous peripheral blood stem cell transplantation is impaired in patients with myeloma
+6
M K Magill, M Drake, S Price, L Ranaghan, S Bridgett, A Jordan, A E Irvine
September 2003
A common polymorphism in the oxygen-dependent degradation (ODD) domain of hypoxia inducible factor-1alpha (HIF-1alpha) does not impair Pro-564 hydroxylation.
+4
Mooney SM, McMullin MF, Flores A, Lappin TR, Lee FS
2003
A randomized trial investigating an iron-rich natural mineral water as a prophylaxis against iron deficiency in pregnancy
+4
Spence D, Haggan SE, McCrum E, Dornan JC, Lappin TR
April 2003
Chuvash-type congenital polycythemia in 4 families of Asian and Western European ancestry
+5
McMullin MF, Jowitt SN, Potter M, Treacy M, Watson WH, Lappin TR
2003
Haemoglobin during pregnancy: relationship to erythropoietin and haematinic status.
+3
White R, Lappin T, Reeves J, MacKenzie G
2003
The cellular biology of erythropoietin receptors
2003
The proteasome: a novel therapeutic target in haemopoietic malignancy
+1
B Walker, A E Irvine
2003
TR.Global down-regulation of HOX gene expression in PML-RAR{alpha}+ acute promyelocytic leukemia identified by small-array real-time PCR
+7
Quinn MF, Grimwade D, O'Neill CM, Ahmed MR, Grimes S, McMullin FM, Cotter FE, Lappin
July 2004
Correlation of TACC3, FGFR3, MMSET and p21 expression with the t(4;14)(p16.3;q32) in multiple myeloma.
+4
Thompson A, Santra M, Barlogie B, Lappin TR, Shaughnessy J Jr
2004
Prognostic Value of C-Reactive Protein and Cytokine Assays for Transplant Related Mortality
+2
M K Magill, L Ranaghan, A E Irvine
2004
Proteasome proteolytic activity in haematopoietic cells from patients with chronic myeloid leukaemia and multiple myeloma
+3
J Lynas, T C M Morris, B Walker, A E Irvine
March 2004
The worldwide distribution of the VHL 598C T mutation indicates a single founding event.
+12
Percy MJ, Amos CI, Guan Y, Shete S, Stockton DW, McMullin MF, Polyakova LA, Ang SO, Pastore YD, Jedlickova K, Lappin TR, Gordeuk V, Prchal JT
2005
Continuous MLL-ENL expression is necessary to maintain immortalization of hematopoietic progenitor cells and establish a “Hox code”
+9
Grier DG, McGonigle GJ, Thompson A, Morrow M, De Silva I, Moulding D, Kioussis D, Lappin TR, Brady HJ, Williams O
March 2005
Disorders of oxidised haemoglobin
+1
McFerran NV, Lappin TR
June 2005
Recessive congenital methaemoglobinaemia: functional characterization of the novel D239G mutation in the NADH-binding lobe of cytochrome b reductase.
+9
Crowley LJ, Davis CA, McMullin MF, Savage G, Hughes J, McMahon C, Quinn RJ, Smith O, Barber MJ, Lappin TR
January 2005
The pathophysiology of HOX genes and their role in cancer.
+4
Thompson A, Kwasniewska A, McGonigle GJ, Halliday HL, Lappin TR
January 2006
A family with erythrocytosis establishes a role for prolyl hydroxylase domain protein 2 in oxygen homeostasis.
+6
Zhao Q, Flores A, Harrison C, Lappin TR, Maxwell PH, McMullin MF, Lee FS
2006
A novel mechanism for BCR-ABL action: stimulated secretion of CCN3 is involved in growth and differentiation regulation
+5
S Price, N Planque, B Perbal, A Pierce, A D Whetton, A E Irvine
2006
Comparative Selectivity and Specificity of the Proteasome Inhibitors BzLLLCOCHO, PS-341 and MG-132
+5
Walker H, Ovaa D, Chauhan K, C Anderson, T C M Morris, A E Irvine
June 2006
Mutation of von Hippel-Lindau Tumour Suppressor and Human Cardiopulmonary Physiology
+14
Brooks JT, Balanos GM, Lappin TR, Layton DM, Leedham DL, Liu C, Maxwell PH, McMullin MF, McNamara CJ, Percy MJ, Pugh CW, Ratcliffe PJ, Talbot NP, Treacy M, Robbins PA
March 2006
Pre-operative plasma erythropoietin concentration and survival following surgery for non-small cell lung cancer
+2
Lappin TR, Maxwell P, Graham AN
September 2007
A novel erythrocytosis-associated PHD2 mutation suggests the location of a HIF binding groove.
+4
Furlow PW, Beer PA, Lappin TR, McMullin MF, Lee FS
2007
Erythropoietin receptor expression in non-small cell lung carcinoma: a question of antibody specificity
+6
Maxwell P, Graham AN, Yakkundi A, Dunlop EA, Shi Z, Johnston PG, Lappin TR
2007
Impaired downregulation following erythropoietin receptor activation in non-small cell lung carcinoma
+1
Maxwell AP, Lappin TR
September 2007
Influence of maternal diabetes mellitus on fetal iron status
+4
Manderson J, Lappin TR, McCance DR, Halliday HL, Sweet DG
November 2007
Pathophysiology of anemia and erythrocytosis
+2
Rainey S, Lappin TR, Maxwell AP
September 2007
Pyruvate kinase deficient hemolytic anemia in the Northern Irish population
+11
van Wijk R, Haggan S, Savage GA, Boyd K, Dempsey S, Hamilton J, Kettle P, Kyle A, Shepherd CW, van Solinge WW, Lappin TR, McMullin MF
April 2007
Warning flags for erythropoiesis-stimulating agents and cancer-associated anemia.
+1
Maxwell AP, Johnston PG
2008
Genomics in Hemato-Oncology: The paradigm of acute myeloid leukaemia
January 2008
A gain-of-function mutation in the HIF2A gene in familial erythrocytosis
+5
Furlow PW, Lucas GS, Li X, Lappin TR, McMullin MF, Lee FS
2008
Allogeneic bone marrow transplant in Belfast- An outcome overview of the first 25 years.
+4
Yates E, Marley C, Piggott S, McMullin MF, Jones FGC
2008
An international standardization program towards the application of gene expression profiling in routine leukaemia diagnostics: The MILE Study pre-phase
+22
TJ Kipps, LZ Rassenti, JR Downing, SA Shurtleff, KI Mills, AF Gilkes, WK Hofmann, G Basso, M Campo Dell’Orto, R Foà, S Chiaretti, J De Vos, S Rauhut, PR Papenhausen, JM Hernández, Lumbreras, AE Yeoh, ES Koay, R Li, WM Liu, PM Williams, L Wieczorek, T Haferlach
2008
Assessment of aspirin resistance varies on a temporal basis in patients with ishaemic heart disease.
+2
Patterson C, McMullin MF, McKeown PP
November 2008
Assessment of the role of timing of second transplantation in multiple myeloma by multistate modeling.
+1
J Apperley, C Morris
March 2008
Bortezomib, Doxorubicin and Dexamethasone (PAD) front-line treatment of Multiple Myeloma
+8
HE Oakervee, S Hallam, N Curry, L Odeh, N Foot, DL Esseltine, M Drake, C Morris, JD Cavenagh
November 2008
Clarithromycin with low dose Dexamethasone and Thalidomide (CDT) is effective therapy in relapsed/refractory myeloma
+8
PJ Kettle, M Drake, DR Hull, C Boyd, FCG Jones, A Morris, P Clarke, P O’Reilly, J Quinn
January 2006
HOX genes: seductive science, mysterious mechanisms.
+2
Grier DG, Thompson A, Halliday HL
2006
Induction of Signalling in Non-Erythroid Cells by Pharmacological Levels of Erythropoietin
+3
Percy MJ, Boland MP, Maxwell AP, Lappin TR
2006
Integration of local and central laboratory functions in worldwide multicentre study. Experience from the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study
+3
Smye M, Sheridan B, Lappin TR, Trimble ER
2008
Clinical and molecular characterisation of a prospectively collected cohort of children and adolescents with polycythaemia vera
+9
Schwarz K, Herter JM, Komrska V, McMullin MF, Minkov M, Niemeyer C, Pospisilova D, Reinhard D, Debatin KM, Pahl H
May 2008
Familial erythrocytosis arising from a gain-of-function mutation in the HIF2A gene of the oxygen sensing pathway.
July 2008
Familial erythrocytosis: molecular links to red blood cell control
+0
Lee FS
March 2008
Further evidence that antigen selection shapes the Ig repertoire in CLL.
2008
G-CSF increases proteasome activity in myeloid cells
+3
P Windrum, MF Mc Mullin, B Walker, AE Irvine
2008
Gene expression profiling for the diagnosis and prognosis of acute myeloid leukaemia. Frontiers in Biosciences
May 2008
Grappling with the HOX network in hematopoiesis and leukemia
+1
Lappin TR, Thompson A
2008
Heat shock protein 90 inhibition is cytotoxic to primary AML cells expressing mutant FLT3 and results in altered downstream signalling
+4
EJ Walsby, AF Gilkes, KI Mills, AK Burnett, C Rowntree
2008
How would I manage a case of essential thrombocythaemia presenting with an ischaemic toe
+0
McMullin MF
2008
Integration of conventional cytogenetics (G-banding), comparative genomic hybridization (CGH) and interphase fluorescence in situ hybridization (i-FISH) for the detection of genomic rearrangements in acute leukaemia
+4
Campbell S, Cuthbert R, Jones FGC, McMullin MF, Humphreys M
2008
Investigation of molecular markers in the diagnosis of refractory celiac disease in a large patient cohort
+10
Abuzakouk M, O’Morain C, O’Donoghue D, Sheahan K, Watson P, O'Brian S, Alexander D, Catherwood M, Jackson J, Kelly J, Feighery C
2008
Lack of association of the heparanase gene single nucleotide polymorphism Arg307Lys with acute lymphoblastic leukaemia in patients from Northern Ireland.
+1
McMullin MF, Catherwood M A
2008
Low-dose thalidomide in myelofibrosis
+4
Reilly JT, McMullin MF, Curtin NJ, Radia D, Harrison CN
2008
Mutated IGHV1-69 gene usage represents a distinct subgroup associated with indolent disease in chronic lymphocytic leukaemia
+3
Catherwood MA, Matthews C, Morris TCM, Alexander HD
2008
Mutation of the von Hippel-Lindau gene alters human cardiopulmonary physiology.
+14
Brooks JT, Balanos GM, Lappin TR, Layton DM, Leedham DL, Liu C, Maxwell PH, McMullin MF, McNamara CJ, Percy MJ, Pugh CW, Ratcliffe PJ, Talbot NP, Treacy M, Robbins PA
October 2008
NADH-cytochrome b5 reductase in a Turkish family with recessive congenital methaemoglobinaemia type I.
+0
Aslan D
June 2008
Novel exon 12 mutations in the HIF2A gene associated with erythrocytosis
+10
Beer PA, Campbell G, Dekker AW, Green AR, Oscier D, Rainey MG, van Wijk R, Wood M, Lappin TR, McMullin MF, Lee FS
2008
Nuclear factor-kappaB as a potential therapeutic target for the novel cytotoxic agent LC-1 in acute myeloid leukaemia
+2
KI Mills, Hewamana S, Gilkes A et al
2008
Primary Plasma Cell Leukaemia And Autologous Stem Cell Transplantation
+4
Curly Morris, Jane F Apperley, Dietger Niederwieser, Bo Bjorkstrand, Gosta Gahrton
2008
Proteasome Inhibitors: A therapeutic strategy for haematological malignancy
+1
B Walker, AE Irvine
May 2008
Recessive congenital methaemoglobinaemia: cytochrome b(5) reductase deficiency
+0
Lappin TR
2008
Reply to Ostrovsky et al.
+1
McMullin MF, Catherwood M A
2008
The Aurora kinase inhibitors AZD1152-HQPA and ZM447439 result in growth arrest and polyploidy in AML cell lines and primary AML blasts
+4
V Walsh, AF Gilkes, CJ Pepper, AK Burnett, KI Mills
2008
The classification and diagnosis of erythrocytosis
2008
The therapeutic potential of the proteasome in leukaemia
+2
Mc Mullin MF, Walker B, Irvine AE
2008
Use Of Imatinib In Elderly Patients In Northern Ireland: Evidence Of Comparable Haematological And Molecular Responses To Younger Patients
+3
AE Irvine, RJG Cuthbert, M Humphries, MF McMullin
2008
Use of imatinib mesylate in elderly patients in Northern Ireland: Evidence of comparable haematological and molecular responses to younger patients
+3
Irvine AE, Cuthbert RJG, Humphreys MW, McMullin MF
2008
WTX is rarely mutated in acute myeloid leukemia
+5
Virappane P, Alikian M, Stasevich I, Mills K, Lister A T, Fitzgibbon J
November 2009
A new polycythaemia vera-associated SOCS3 SH2 mutant (SOCS3F136L) cannot regulate erythropoietin responses
+7
Elliott J, Percy MJ, Inami M, Attal H, Harrison CN, Inokuchi K, McMullin MF, Johnston JA
2009
A novel L218P mutation in NADH-cytochrome b5 reductase associated with type I recessive congenital methemoglobinemia.
+5
Yarali N, Kara A, Bay A, Bozkaya IO, Tunc B, Percy MJ
2009
A Rapid And Sensitive Method For Measuring Cell Adhesion
+1
Lynn McCallum, Alexandra E Irvine
2009
ABCB1 (MDR1) rs1045642 is associated with increased overall survival in plasma cell myeloma
+5
Catherwood MA, Hodkinson CF, Kettle PJ, Drake M, Morris TCM, Alexander HD
August 2009
Blister-like aneurysm of the anterior communicating artery
+0
Brophy BP
2009
British Society for Haematology Slide Session , annual scientific meeting, Glasgow
+12
Burthem J, Bisland M, Carey P, Crotty G, Devalia V, Janda B, Gordon W, Harrison CN, Murray J, Shelbak A, Thomas A, Wilkins B, McMullin MF
2009
CCN3- A Key Regulator of the HaemopoieticCompartment
+0
AE Irvine
2009
CCN3: a key growth regulator in Chronic Myeloid Leukaemia
+4
Wanhua Lu, Susan Price, Noureddine Lazar, Bernard Perbal, Alexandra E Irvine
2009
CCN3: a NOVel growth factor. In: Neoplastic Transformation, Diagnosis and Therapeutic Strategy
+1
L Mc Callum, AE Irvine
2009
Changes in microRNA expression in acute myeloid leukaemia cell lines when treated with an inhibitory dose of 5-aza-2’-deoxycytidine, a DNA methylation inhibitor
+2
H Colyer, M Dellett, KI Mills
2009
Clinical and haematological presentation of children and adolescents with polycythaemia vera.
+1
McMullin MF, Pahl HL
2009
Clonal diversity in the myeloproliferative neoplasms: independent origins of genetically distinct clones.
+13
Jones AV, Bench AJ, Goday-Fernandez A, Boyd EM, Vaghela KJ, Erber WN, Obeh B, Wright C, McMullin MF, Cullis J, Huntly BJP, Harrison CN, Cross CP, Green AR
2009
Complete array of HOX gene expression by RQ-PCR.
+1
Lappin TR, Thompson A
2009
Comprehensive Genomic Screens Identify a Role for PLZF-RAR as a Positive Regulator of Cell Proliferation via Direct Regulation of c-MYC
+8
I Hormaeche, S Doulatov, JM Flatow, D Grimwade, KI Mills, C Ambardekar, MJ McConnell, JE Dick, JD Licht
2009
Defining the landscape of resistance mutations in the context of modern treatment protocols for acute promyelocytic leukaemia
+9
F Guidez, F Ravandi, E Duprez, M Patel, K Mills, M Aldouri, M Auger, AK Burnett, E Solomon, D Grimwade
October 2009
Dramatic resolution of respiratory symptoms with imatinib mesylate in patients with chronic myeloid leukemia presenting with lower airway symptoms resembling asthma
+4
McNicholl F, Furby D, Richardson D, Cuthbert RJ, McMullin MF
2009
Effective use of imatinib-mesylate in the treatment of relapsed CML after allogeneic transplantation
+4
Shaun R McCann, Stephen Langabeer, Sandra Irvine, Mary Frances McMullin, Eibhlin Conneally
2009
Elevated expression of the leukemia associated antigen SSX2IP predicts survival in acute myeloid leukemia patients who lack detectable cytogenetic rearrangements
+2
J Greiner, M Schmitt, KI Mills
2009
Erythrocytosis –associated Hif-2alpha mutations demonstrate a critical role for residues C-terminal to the hydroxylacceptor praline
+6
Percy MJ, Sutherland S, Bierl C, McMullin MF, Master SR, Lappin TR, Lee F
2009
Erythrocytosis associated with a novel missense mutation in the HIF2A gene.
+5
Sutherland S, Van Wesel AC, Huizinga EG, Percy MJ, Bierings M, Lee FS
January 2009
Genetic origins and clinical phenotype of familial and acquired erythrocytosis and thrombocytosis
+0
Rumi E
2009
Global methylation changes in acute myeloid leukaemia cell lines after treatment with a demethylating agent identifies candidate genes for investigation into restored expression
+1
M Dellett, KI Mills
2009
Hoxa6 potentiates short-term hemopoietic cell proliferation and extended self-renewal.
+3
A Kwasniewska, KI Mills, TRJ Lappin, A Thompson
September 2009
Identification of high oxygen affinity hemoglobin variants in the investigation of patients with erythrocytosis
+7
Butt NN, Crotty GM, Drummond MW, Harrison C, Jones GL, Turner M, Wallis J, McMullin MF
2009
Idiopathic erythrocytosis: a disappearing entity
October 2009
Laparoscopic duodenojejunostomy for superior mesenteric artery syndrome–how I do it
+1
Devitt PG, Thompson SK
May 2009
Microarray classification of myelodysplastic syndrome (MDS) identifies subgroups with distinct clinical outcomes and identifies patients with high risk of AML transformation
+10
A Kohlmann, PM Williams, L Wieczorek, W-M Liu, R Li, W Wen, DT Bowen, H Loeffler, JM Hernandez, W-K Hofmann, T Haferlach
2009
Proteasome proteolytic activity is linked to BCR-ABL expression
+7
Windrum P, Magill L, Melo JV, McCallum L, McMullin MF, Ovaa H, Walker B, Irvine AE
February 2009
Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development.
+2
Thompson A, Lappin TR, Halliday HL
2009
Regulation of ABCB1 (p-glycoprotein) by the FOXO1 Transcription Factor in Acute Myeloid Leukemia
+6
S Ahluwalia, KI Mills, M Grundy, S Shang, AK Burnett, NH Russell, M Pallis
2009
Report on the fifth international workshop on the CCN family of genes
+1
Perbal B, Yeger H
2009
Response criteria for essential thrombocythemia and polycythaemia. Result of a European LeukemiaNet (ELN) consensus conference.
+11
Birgegard G, Finazzi G, Greisshammer M, Harrison C, Hasselbalch H, Kiladijan J J, Lengfelder E, McMullin MF, Passamonti F, Reilly JT, Vannucchi AM, Barbui T
2009
Snippets in Surgical pathology
+0
McMullin MF
2009
Socs3 tyrosine phosphorylation as a potential bio-marker for myeloproliferative noeoplasms associated with mutant JAK2 kinases
+6
Suessmuth Y, Scott LM, Nahlik K, McMullin MF, Constantinescu SN, Green AR, Johnston JA
August 2009
Sustained response of primary cutaneous CD30 positive anaplastic large cell lymphoma to bexarotene and photopheresis
+2
Catherwood M, Pettengell R, Morris TC
2009
The Clinical Utility of Microarray-Based Gene Expression Profiling in the Diagnosis and Subclassification of Leukemia: Report on 3248 Cases from the International MILE Study Group
+23
A Kohlmann, L Wieczorek, G Basso, G te Kronnie, M-C Béné, J de Vos, EA Macintyre, C Preudhomme, JM Hernández, W-K Hofmann, KI Mills, AF Gilkes, S Chiaretti, JR Downing, SA Shurtleff, TJ Kipps, LZ Rassenti, AE Yeoh, ES Koay, PR Papenhausen, W-M Liu, P Xiang, PM Williams, R Foà
August 2009
The finding of a reciprocal whole-arm translocation t(X;12)(p10;p10) in association with atypical chronic myeloid leukaemia.
+3
McMullin MF, Humphreys MW, Hamilton J, McGrattan P
2009
The impact of dose escalation and resistance modulation in older patients with acute myeloid leukaemia and high risk myelodysplastic syndrome: the results of the LRF AML 14 trial
+9
Milligan D, Goldstone A, Prentice A, McMullin MF, Dennis M, Sellwood E, Pallis M, Russell N, Hills RK, Wheatley K
2009
The novel tubulin-targeting agent pyrrolo-1,5-benzoxazepine-15 induces apoptosis in poor prognostic subgroups of chronic lymphocytic leukemia
+11
Maginn EN, Greene LM, McGuckin S, Hayat A, Browne PV, Butini S, Campiani G, Catherwood MA, Vandenberghe E, Williams DC, Zisterer DM, Lawler M
March 2009
Vitamin D deficiency and insufficiency in pregnant women: a longitudinal study
+3
Barnes MS, Alexander HD, McFaul P, Wallace JM
2010
Application of connectivity mapping in predictive toxicology based on gene-expression similarity.
+1
Gant T W, Zhang S D
2015
Expressional and Mutational Signature of Cohesin mutations in Myeloid Leukaemia Cell lines
+2
Liberante FG, Mills KI, Thompson A
2017
Separation and Enrichment of Hematopoietic Stem Cells for CCN Studies.
+0
Irvine AE
Identification of Genes Whose Expression Overlaps Age Boundaries and Correlates with Risk Groups in Paediatric and Adult Acute Myeloid Leukaemia
June 2020
The Molecular Landscape of AML
+1
Clarke K, Mills K
June 2020
P2X7 receptor signalling in normal and cancer urothelial cells
+2
McCloskey K, Breen C, McKerr N
June 2020
The E3 ligase HUWE1 inhibition as a therapeutic strategy to target MYC in Multiple Myeloma
+11
Campbell DC, Morgan JJ, Lawson MA, Down JM, Chauhan D, McAvera RM, Morris TC, Hamilton C, Krishnan A, Rajalingam K, Chantry AD, Irvine AE
July 2020
The DNA Damage Repair Response
+0
Mills K
August 2020
The friendly side of snakes: Can snake venom provide treatment for blood cancer?
2021
New targets for therapy antigen identification in adults with B-cell acute lymphoblastic leukaemia
+6
Cooksey L, Freire Boullosa L, Van Tendeloo V, Smits E, Mills K I , Orchard KH, Guinn BA
September 2020
Modification of the Histone Landscape with JAK Inhibition in Myeloproliferative Neoplasms
+5
McPherson S, Smith J, Mead A, Harrison C, Mills K, McMullin MF
September 2020
Identification of Genes Whose Expression Overlaps Age Boundaries and Correlates with Risk Groups in Paediatric and Adult Acute Myeloid Leukaemia
+2
Mills K, Orchard KH, Guinn BA
September 2020
Chronic loss of STAG2 leads to altered chromatin structure contributiong to de-regulated transcription in AML
+6
Lappin K, Craig S, Liberante F, McDade S, Thompson A, Mills K, Savage K
December 2020
Characterisation of the effect of novel anti-cancer components of Pseudechis australis and Crotalus vegrandis snake venom on acute lymphoblastic leukaemia cells.
+4
McCloskey K, Mills K, Dobbin S, Cobice D, McClean S
October 2020
A compound combination screening approach with potential to identify new treatment options for paediatric acute myeloid leukaemia
+4
Davies L, Matchett K, Ge Y, Mills K, Blayney J
May 2021
The Impact of Epigenetic Modifications in Myeloid Malignancies
+1
Mohd-Sarip A, Mills KI
October 2021
Survivin’ acute myeloid leukaemia—a personalised target for inv(16) patients
+6
Brown E, Bullinger L, Hills RK, Morris V, Döhner H, Mills KI, Guinn B
September 2021
Significance of NPM1 Gene Mutations in AML
+2
Catherwood MA, McMullin MF, Mills KI
September 2021
Purification of novel phospholipase A2 enzymes with anticancer activity from Pseudechis australis snake venom
+6
Bann S, Cochrane S, Cobice D, McClean S, Jordan A, McCloskey K, Mills K
May 2021
Protein tyrosine phosphatase receptor type C (PTPRC or CD45)
+2
Ali A, McMullin MF, Mills K
February 2021
Patients with triple-negative, JAK2V617F- and CALR-mutated essential thrombocythemia share a unique gene expression signature
+18
Villiers W, Dillon R, Simpson M, Runglall M, Smith A, Chatzikyriakou P, Lavender P, Kanda A, Mills K, Bellosillo Paricio B, Kaufman-Cook J, Ord S, Kordasti S, Radia D, Woodley C, Francis Y, Mufti G, McLornan DP, Harrison CN
March 2021
NEMHESYS-European Perspective on the Implementation of Next-generation Sequencing Into Clinical Diagnostics
+8
Clarke KM, Rodríguez-Vicente AE, McGimpsey JE, Abáigar M, Díez CB, Benito R, Bullinger L, Mills KI, Hernández Rivas JM
September 2021
Multiplex Screening for Interacting Compounds in Paediatric Acute Myeloid Leukaemia
+4
Lappin KM, Mutch A, Ali A, Matchett KB, Mills KI
June 2021
Molecular pathogenesis of the myeloproliferative neoplasms
+1
McMullin MF, Mills K
January 2021
Erythropoietin in bone homeostasis-Implications for efficacious anemia therapy
+1
Mills KI, Lappin T
June 2022
TP53 Mutations Identified Using NGS Comprise the Overwhelming Majority of TP53 Disruptions in CLL: Results From a Multicentre Study
+17
Chiecchio L, Cavalieri D, Donaldson D, Lawless,S, ElHassadi E, Hayat A, Cahill MR, O’Shea D, Sargent J, Stewart P, Maurya M, Quinn J, Murphy P, de Castro DG, Mills K, Cross NCP, Forconi F, Iyengar S
March 2022
Cancer-Associated SF3B1 Mutations Confer a BRCA-Like Cellular Phenotype and Synthetic Lethality to PARP Inhibitors
+10
Barros EM, Jhujh SS, Irwin GW, McMillan H, Liberante FG, Latimer C, LaBonte MJ, Mills KI, Harkin DP, Stewart GS, Savage KI
